Endocrine Abstracts

Introduction: Obesity is associated with an increasing risk of diabetes and atherosclerosis. Previous studies in animals show that oxidized low-density lipoprotein (Ox-LDL) can be captured by the adipocyte through different scavenger receptors (SR) and thus contribute to the worsening of insulin resistance (IR). We analyze the association between Ox-LDL levels and different SR present in adipose tissue and their relationship with the presence of obesity and insulin resistance ...

Introduction: HIF-1α, a hypoxia marker, is an important factor for transcriptional regulation of cell metabolism and the adaptation to cellular stress. It modulates the function of phagocytic cells by stimulating surface receptors such as scavenger receptors. But little is known on their relationship in adipose tissue, whose increase has been associated with an increased risk of atherosclerosis. The aim of this study is to analyze in adipose tissue the association between...